San Francisco Startup Scene
Explore the San Francisco, California startup ecosystem with 261 investors and startups. Our directory features 256 angel investors and VCs alongside 5 startups actively building in San Francisco. 25 investors have made recent investments, and 0 startups are generating revenue.
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Startups (5)
View all California startups →Aten Security
Nyah Check
San Francisco, CA
AI agents act with production credentials, but nothing decides each action and nobody can say who authorized it.
Parkzy
Vala Makhfi
San Francisco, California
Drivers and AV fleets waste time and miles searching for parking while residential parking spots sit empty; 'Airbnb for parking' models fail due to high host effort.
Deep Blue Medical
Bill Perry
San Francisco, California
Surgical soft tissue repairs often fail as sutures cut through tissue or mesh at anchor points, causing pain, dehiscence, hernia recurrence, and reoperations.
MediSynth AI
Dr. Sarah Chen
San Francisco, CA
Clinical trials struggle to find and enroll eligible patients quickly; lengthy enrollment timelines and high costs.
Investors (256)
View all California investors →CrossLayer Capital Fund
CrossLayer Capital Fund
San Francisco, California
Quiet Access
Quiet Access
San Francisco, California
Lexi Ventures Fund
Lexi Ventures Fund
San Francisco, California
HCM S5Aiv
HCM S5Aiv
San Francisco, California
Quiet SH
Quiet SH
San Francisco, California
GGF
GGF
San Francisco, California
Foreground Capital Fund
Foreground Capital Fund
San Francisco, California
Capra Ventures H1
Capra Ventures H1
San Francisco, California
Radicle Impact Opportunity Fund
Radicle Impact Opportunity Fund
San Francisco, California
Artis TechBio Multiclass
Artis TechBio Multiclass
San Francisco, California
Pier 88 Growth Equity Fund IV - Hydro-Blok
Pier 88 Growth Equity Fund IV - Hydro-Blok
San Francisco, California
HCM S19A
HCM S19A
San Francisco, California
Chispa VC Kapitalex, a series of Decile
Chispa VC Kapitalex, a series of Decile
San Francisco, California
Fabian Hediger
Studio Alpha
San Francisco, CA
Application-layer AI for business (enterprise and SMB); accelerator running batches of five companies with weekly 30-minute founder sessions; invests only in teams of two or three founders; typical...
Novera Holdings
Novera Holdings
San Francisco, California
Novera Ventures
Novera Ventures
San Francisco, California
HCM S15Aiii
HCM S15Aiii
San Francisco, California
Overlook Fund
Overlook Fund
San Francisco, California
Alta Partners
Alta Partners
San Francisco, CA
Alta Partners is a leading venture capital firm in life sciences, funding over 130 companies in the industry since 1996. Their diverse and integrated team brings together a powerful depth of...
ACP Kin
ACP Kin
San Francisco, California
GreatPoint Ventures Innovation Fund
GreatPoint Ventures Innovation Fund
San Francisco, California
Republic S Ventures Velvet, a Series of Republic Ventures SPVs
Republic S Ventures Velvet, a Series of Republic Ventures SPVs
San Francisco, California
HCM S17B
HCM S17B
San Francisco, California
Standard Capital Ventures Fund
Standard Capital Ventures Fund
San Francisco, California
Chaotica Fund
Chaotica Fund
San Francisco, California
OpenAI Startup Fund
OpenAI Startup Fund
San Francisco, California
Articulate Venture Capital Fund
Articulate Venture Capital Fund
San Francisco, California
Position Ventures
Position Ventures
San Francisco, California
DC, a series of Platform Fund
DC, a series of Platform Fund
San Francisco, California
Outset Capital Fund
Outset Capital Fund
San Francisco, California
Point Olema U.S. Venture Capital Portfolio
Point Olema U.S. Venture Capital Portfolio
San Francisco, California
Biotechnology Value Fund
Biotechnology Value Fund
San Francisco, CA
Biotechnology Value Fund, L.P. is an evergreen fund specializing in early stage financing. It focuses on undervalued investment opportunities in the biotechnology sector.
Clean Pacific Ventures
Clean Pacific Ventures
San Francisco, CA
[Clean Pacific Ventures](http://www.cleanpacific.com) invests in early stage clean technology companies.
Rothenberg Ventures
Rothenberg Ventures
San Francisco, CA
Rothenberg Ventures invests in technology-enabled, scalable, asset-light entrepreneurs.
Pyramid Technology Ventures
Pyramid Technology Ventures
San Francisco, CA
Pyramid is a leading San Francisco-based venture capital firm that partners with talented entrepreneurs to help build market leading, successful businesses. Their partners have been successfully...
General Inception
General Inception
San Francisco, CA
Deep tech venture studio that partners as a business co-founder with scientific founders to translate foundational science into companies across engineered biology, life science tools & diagnostics,...
i/o Ventures
i/o Ventures
San Francisco, CA
i/o ventures is an early stage startup program that focuses heavily on its mentorship. We work closely with founders from product launch through the next stage of company development, sharing what...
Subtraction Capital
Subtraction Capital
San Francisco, CA
Subtraction Capital is a venture fund providing financial support to entrepreneurs.
Thomas Weisel Venture Partners
Thomas Weisel Venture Partners
San Francisco, CA
Thomas Weisel Venture Partners (TWVP) is an early stage venture capital firm that invests in emerging information technology companies. As a partner with a long-term perspective, TWVP plays an...
Right Side Capital Management
Right Side Capital Management
San Francisco, CA
RightSide Capital Management is a San Francisco based firm, targeting seed-stage startups. They plan to have 100-200 investments per year, give completely standard terms, have no face-to-face...
Morgan Stanley Expansion Capital
Morgan Stanley Expansion Capital
San Francisco, CA
Boom Capital Ventures
Boom Capital Ventures
San Francisco, CA
Invests early in founders building at the frontiers of science: healthcare, genomics, machine intelligence, aerospace and new chemistries.
Bloomberg Beta
Bloomberg Beta
San Francisco, CA
Bloomberg Beta is an early-stage fund, backed by Bloomberg L.P., that invests and makes companies. They focus on areas that are broadly of interest to Bloomberg, but choose investments...
Top Tier Capital Partners
Top Tier Capital Partners
San Francisco, CA
Chess Ventures
Chess Ventures
San Francisco, CA
[Chess Ventures](http://www.chessventures.com) is a private equity firm that invests in earlier-stage technology companies that have direct application to the financial services industry.
Breakout Labs
Breakout Labs
San Francisco, CA
Breakout Labs is the Thiel Foundations newest program. Through Breakout Labs, were reshaping the way early-stage science is funded, so that early-stage companies can advance their most radical...
Obvious
Obvious
San Francisco, CA
The Obvious Corporation creates technology systems to facilitate the process of collaboration between people to improve the world. Obvious believes that technology has the power to affect...
Triage Ventures
Triage Ventures
San Francisco, CA
Script Capital
Script Capital
San Francisco, CA
Early-stage internet and software startups. Partner with technical founders. Typical checks $250k-$500k. Emphasizes curiosity, rapid iteration, and founder support including sabbaticals and student...
Heights Capital Management
Heights Capital Management
San Francisco, CA
Heights Capital Management, Inc. is a private equity firm specializing in private investments in public equity in emerging growth companies. The firm typically invests in healthcare and technology...
Explore California
About San Francisco's Startup Scene
San Francisco, California has 256 investors and 5 startups in our community. 25 investors are actively deploying capital.
Popular sectors in San Francisco include FINTECH, AI ML, B2B SAAS.
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Ben Wiggins
7x Founder · 1 Exit · Experienced Angel Investor · CIO Family Office
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