The Startup Scene in Indiana

Browse the Indiana startup ecosystem featuring 21 investors and startups. Our directory includes 21 angel investors and VCs with an average check size of $12.0M, plus 0 startups across all sectors. 4 investors are actively investing, and 0 startups are generating revenue.

21
Investors
0
Startups
$12.0M
Avg Check
0%
With Revenue
Indianapolis
Top City
19%
Active Investors

Pearl Street Venture Funds

Pearl Street Venture Funds

VC

Indianapolis, IN

Check: $6.7M – $7.5M

Pearl Street Venture Funds is an Indiana-based venture capital fund investing in innovative life sciences companies to provide superior financial returns for its limited partners.

Exploring6 portfolio co.

FLYWHEEL FUND

FLYWHEEL FUND

VC

Bloomington, Indiana

Check: $30K – $150K
Exploring

Heron Capital

Heron Capital

VC

Carmel, IN

Check: $4.0M – $46.0M

Heron Capital is a venture capital fund dedicated to investing in mid and growth stage companies focused on the life sciences, including therapeutic medical devices, diagnostics and healthcare...

Exploring7 portfolio co.

Gravity Ventures

Gravity Ventures

VC

Indianapolis, IN

Check: $365K – $5.0M

Gravity Ventures is a committed, member-managed angel capital fund - designed to capitalize on the growth in entrepreneurial activity and venture financing, throughout the state of Indiana and the...

Exploring48 portfolio co.

CHV Capital

CHV Capital

VC

Indianapolis, IN

Check: $2.8M – $8.0M

CHV Capital, Inc. (CHV) is an early-stage investor focused on building value in business opportunities that serve a business or clinical need in the market. They are a return-driven venture capital...

Exploring3 portfolio co.

Capital Group

Capital Group

VC

IN

Check: $40.0M – $120.0M

It's about the investor. Individuals, families, businesses and institutions look to Capital Group's companies to guard and grow their hard-earned money. Whether in North America, Europe or Asia,...

Exploring57 portfolio co.

CID Equity Capital

CID Equity Capital

VC

Indianapolis, IN

Check: $12.0M – $27.5M

CID Capital’s Private Equity Group makes majority investments in lower-middle-market companies with a strong history of consistent performance. Their focus is on companies that have the potential...

Exploring38 portfolio co.

HALO Capital Group

HALO Capital Group

VC

Indianapolis, IN

Check: $1.0M – $1.1M

HALO Capital Group is a central Indiana based seed funding organization. We are a formal group of more than 20 former and current executives who are interested in investing their time and money into...

Exploring2 portfolio co.

Allos Ventures

Allos Ventures

VC

Carmel, IN

Check: $4.0M – $15.8M

In Indiana, Ohio, and the surrounding region, there is a significant gap between the number of early-stage companies seeking venture capital and the amount of venture capital targeting such...

Exploring13 portfolio co.

Elevate Ventures

Elevate Ventures

VC

Indianapolis, IN

Check: $50K – $1.8M

Elevate Ventures nurtures and develops emerging and existing high-potential businesses into high-performing, Indiana-based companies. We accomplish this by providing rigorous business analysis and...

Exploring326 portfolio co.

Start Something Ventures

Start Something Ventures

Syndicate

Indianapolis, IN

Check: $50K – $200K
B2B SAASAPIS AND PLATFORMS

We invest in SaaS or tech-enabled businesses with proven revenues, typically with valuations between $2M and $10M. Focus is on early stage (pre-seed and seed) using SPVs to pool investments. Industry...

Exploring49 portfolio co.

Blue Sky Capital

Blue Sky Capital

VC

New Albany, IN

Check: $100K – $1.0M

Seed capital for high-growth deep tech companies in semiconductor, photonics, electronics and post-silicon materials and related manufacturing technologies.

Exploring24 portfolio co.

VisionTech Angels

VisionTech Partners, LLC

Syndicate

Indianapolis, IN

Check: $200K – $500K
BIO HEALTHCAREMEDICAL DEVICESDIGITAL HEALTH+5

VisionTech Angels is a Midwest-focused angel investing network based in Indianapolis, IN. Over the last decade-plus, it has become one of the region’s most active angel groups, investing in...

Exploring

BioCrossroads

BioCrossroads

VC

Indianapolis, IN

Check: $285K – $300K

BioCrossroads is a venture capital firm specializing in life sciences investments. The firm launches new life sciences businesses, expands science education, and expands collaboration activities and...

Exploring2 portfolio co.

Twilight Venture Partners

Twilight Venture Partners

VC

Indianapolis, IN

Check: $1.0M – $15.0M

Twilight Venture Partners invests exclusively in early-stage biotech and med tech companies. Their Partners each have CEO-level experience, which they leverage to select outstanding companies and...

Exploring1 portfolio co.

Clarian Health Ventures

Clarian Health Ventures

VC

Indianapolis, IN

Check: $2.8M – $20.5M

A return-driven venture capital fund, Clarian Health Ventures (CHV) is guided by the strategic objectives and mission of Clarian Health, Indiana's largest health care system. These objectives include...

Exploring3 portfolio co.

Spring Mill Venture Partners

Spring Mill Venture Partners

VC

Carmel, IN

Check: $3.0M – $12.0M

Spring Mill Venture Partners is an early stage venture capital firm focused on investing in high-growth information technology and life sciences companies located in Indiana and the surrounding...

Exploring5 portfolio co.

Cultivian Ventures

Cultivian Ventures

VC

Carmel, IN

Check: $1.5M – $18.2M
AGRITECHFOOD TECH

Cultivian Ventures, LP, is a venture capital fund focused on high technology opportunities in the food and agricultural sectors. Cultivian operates from the US Midwest, which hosts the planet's...

Exploring42 portfolio co.

Lilly Ventures

Lilly Ventures

VC

Indianapolis, IN

Check: $3.0M – $44.0M

Lilly Ventures is the venture capital arm of Eli Lilly and Company responsible for life science investing in North America and Europe. Our primary goal is to facilitate the success of companies in...

Exploring68 portfolio co.

VisionTech Partners

VisionTech Partners

Angel

Indianapolis, Indiana

Check: $5K – $500K
AI MLBIO HEALTHCAREMEDICAL DEVICES+4

Midwest-focused angel investing network (VisionTech) that sources and diligences early-stage/early-growth technology companies. Focus areas include life sciences, medical devices, SaaS, IoT, advanced...

Exploring

Innovatemap

Innovatemap

VC

Indianapolis, IN

Check: $10K – Varies
FINTECHB2B SAAS

Innovatemap Ventures backs product-minded founders building high-growth, design-led, tech-enabled businesses—with emphasis on B2B SaaS and fintech/financial software verticals where product, UX, and...

Exploring20 portfolio co.

Explore Indiana

About the Indiana Startup Ecosystem

Indiana is home to a thriving startup ecosystem with 21 investors and 0 startups in our directory. Key hubs include Indianapolis, Carmel, Bloomington.

The most active sectors in Indiana include B2B SAAS, BIO HEALTHCARE, MEDICAL DEVICES. 4 investors have made recent investments, showing strong capital deployment activity in the region.

Local investors offer advantages beyond capital — regional network effects, knowledge of local market dynamics, and introductions to customers and partners. Geographic proximity often leads to more engaged board members and advisors.

Frequently Asked Questions

How many investors and startups are in Indiana?
We track 21 investors and 0 startups in Indiana. 4 investors have made recent investments, and 0 startups are generating revenue.
What is the typical check size for investors in Indiana?
The average check size among investors in Indiana is $12.0M. Check sizes vary by investor type — angels typically write smaller checks while VCs and funds invest larger amounts.
How do I connect with investors in Indiana?
Upload your pitch deck on The Founders' Group landing page for a free AI analysis. Our matching algorithm considers sector focus, stage fit, check size, location, and thesis alignment to recommend the most relevant investors for your startup.
What sectors are most popular in Indiana?
The most active sectors in Indiana based on our data include B2B_SAAS, BIO_HEALTHCARE, MEDICAL_DEVICES. However, investors and startups in our directory span all major sectors.
Which cities in Indiana have the most startup activity?
The highest concentration of investors and startups in Indiana is in Indianapolis, Carmel, Bloomington. These cities have the strongest local ecosystems for fundraising and startup growth.

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