Investors in Missouri

Browse angel investors and venture capital firms based in Missouri. Our directory features 27 investors in Missouri actively funding startups across all sectors and stages, from pre-seed to growth.

Total Investors

$6.6M

Avg Check Size

Recently Active

St. Louis

Top City

Missouri Investors (27)

AMERICAN CENTURY VENTURE FUND

Kansas City, Missouri

Exploring

Stakehouse Fund I QP

Saint Louis, Missouri

Check: $300K – $1.5M

Exploring

Cultivation Capital AgTech Fund

Saint Louis, Missouri

Check: $200K – $1.0M

Exploring

Cultivation Capital

St. Louis, MO

Check: $100K – $6.5M

ANGELSEEDSERIES B

Cultivation Capital is a venture capital firm managed by team of serial entrepreneurs. The firm's goal is to take revenue-generating businesses to the next level with help from the General Partners....

Exploring9 portfolio co.

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OPENAIR Equity Partners

Kansas City, MO

Check: $1.0M – $105.0M

SEEDSERIES BSERIES A

Exploring7 portfolio co.

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proChain Ventures

Saint Louis, MO

Check: $25K – $1.0M

PRE SEEDSEED

LOGISTICS AND SHIPPINGSUPPLY CHAIN TOOLSIOT+7

proChain Ventures is a specialist venture capital firm investing in pre-seed and seed (pre-Series A) startups transforming global supply chains. Focus on supply-chain-related hard tech and deep tech...

Exploring18 portfolio co.

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Build-A-Bear Workshop

Corporate

Saint Louis, MO

Check: $2.7M – $10.3M

SERIES BSERIES A

Build-A-Bear Workshop In

Exploring1 portfolio co.

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Capital Innovators

Accelerator

Saint Louis, MO

Check: $50K – $1.0M

ACCELERATOR INCUBATORSEEDSERIES A

B2B SAASCONSUMERCLEAN ENERGY+2

Capital Innovators runs top-ranked accelerator programs and manages seed and Series A venture funds focused on technology, consumer products, energy innovations and verticalized corporate accelerator...

Exploring122 portfolio co.

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Rockbridge Growth Equity

Detroit, MO

Check: $7.0M – $7.0M

SEEDSERIES B

Rockbridge Growth Equity is a private equity investor. They have a deep industry expertise, the strategic benefits of "sister companies" , a long-term perspective and a different approach to...

Exploring3 portfolio co.

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Mariner Capital Ventures

St. Louis, MO

Check: $2.4M – $8.0M

SEED

Mariner Capital Ventures (MCV) is a $10 million start-up, angel, and early stage investment fund. MCV targets new and young companies that design innovative and competitive products and services....

Exploring2 portfolio co.

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Razorback Capital

Kansas City, MO

Check: $380K – $6.0M

ANGELSERIES A

Exploring3 portfolio co.

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RiverVest

St. Louis, MO

Check: $750K – $46.0M

SEEDSERIES BSERIES A

RiverVest Venture Partners is a venture capital firm focused on identifying and shaping early-stage life science companies to create significant shareholder value. With hands-on, high-level expertise...

Exploring19 portfolio co.

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Ascension Ventures

Clayton, MO

Check: $226K – $27.0M

ANGELSEEDSERIES B

AHV was established in 2001 by Ascension Health with a commitment of $125 million to invest in expansion- to late-stage healthcare companies. Ascension Health is the nation's largest Catholic and...

Exploring18 portfolio co.

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Arch Grants

Corporate

St. Louis, MO

Check: $50K – $110K

ANGEL

Arch Grants is an international business plan competition established to attract entrepreneurs in any field to launch new, innovative businesses in St. Louis. Grant recipients receive up to $50,000,...

Exploring9 portfolio co.

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St. Louis Arch Angels

St. Louis, MO

Check: $138K – $8.5M

ANGELSEEDSERIES A

The mission of the St. Louis Arch Angels is to provide opportunities for their members to obtain outstanding financial returns by investing in early-stage companies with high growth potential in the...

Exploring11 portfolio co.

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NIPR

Kansas City, MO

Check: $3.7M – $3.9M

SERIES A

National Insurance Producer Registry (NIPR) is a non-profit affiliate of the National Association of Insurance Commissioners (NAIC). NIPR developed and implemented the Producer Database (PDB) and the...

Exploring6 portfolio co.

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Kauffman Foundation

Corporate

Kansas City, MO

Check: $75K – $24.0M

SEED

Kaufman foundation focuses on grant making and operations in the fields of education and entrepreneurship.

Exploring7 portfolio co.

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Missouri Technology Corporation

Jefferson City, MO

Check: $75K – $835K

ANGELSEED

The Missouri Technology Corporation is a public-private partnership created by the Missouri General Assembly to promote entrepreneurship and foster the growth of new and emerging high-tech companies....

Exploring5 portfolio co.

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Think Big Partners

Kansas City, MO

Check: $24K – $2.3M

ANGELSERIES A

Think Big Partners is an early-stage startup accelerator and mentorship-based collaborative network located in Kansas City, Missouri. Think Big Partners has successfully launched or grown over 150...

Exploring3 portfolio co.

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Oakwood Medical Investors

St. Louis, MO

Check: $2.1M – $30.0M

SEEDSERIES B

Oakwood Medical Investors is a life science venture capital fund formed to invest in development stage medical device, biotechnology, pharmaceutical and medical service companies. Target portfolio...

Exploring4 portfolio co.

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Prolog Ventures

St. Louis, MO

Check: $500K – $15.3M

SEEDSERIES BSERIES A

Venture capital firm specializing in life sciences. Since launch in 2001, they have supported more than 25 young companies. Prolog invests in traditional healthcare opportunities as well as emerging...

Exploring20 portfolio co.

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BioGenerator

St. Louis, MO

Check: $75K – $4.0M

ANGELSEEDSERIES B

The BioGenerator, the non-profit venture development organization of BioSTL, facilitates the formation of successful, sustainable bioscience companies in the St. Louis region. It provides start-up...

Exploring31 portfolio co.

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Redbud VC

Missouri

Check: $250K – $400K

PRE SEED

Redbud VC invests first or early in technology startups across North America (US & Canada), with a focus on founders "strengthened by struggle." The firm is managed by Willy and Jabbok Schlacks...

Moderately Active7 portfolio co.

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Melissa Walker

Graematter

St. Louis, MO

Exploring2 portfolio co.

Website LinkedIn

Centennial Investors

Angel

Columbia, MO

Check: $150K – $500K

PRE SEEDSEEDPOST SEED

Centennial Investors is an angel-investing organization based in mid-Missouri. The group provides risk capital to high-potential technology- or science-based startups primarily in Missouri and...

Exploring23 portfolio co.

Website LinkedIn

Daniel Westerheim

Angel

Columbia, MO

Check: $150K – $500K

Centennial Investors is an angel investing group focused on providing risk capital to high-potential, technology- or science-based startups in Missouri and adjoining states. The group seeks to invest...

Moderately Active17 portfolio co.

Website LinkedIn

Brett Calhoun

Redbud VC

Missouri

Check: $250K – $500K

The greatest driver of venture returns is the selection of founders strengthened by struggle. We seek founders who display extraordinary perseverance, prioritize customer discovery, and are...

Exploring4 portfolio co.

Website LinkedIn

About Missouri Investing

Missouri is home to 27 investors in our directory, including 21 VCs, 3 Corporates, 2 Angels, 1 Accelerator. Most are concentrated in St. Louis, Kansas City, Saint Louis.

Local investors can offer advantages beyond capital — including regional network effects, knowledge of local market dynamics, and introductions to regional customers and partners. Many founders find that geographic proximity leads to more engaged board members and advisors.

Frequently Asked Questions

How many Missouri investors are in this directory?

We currently track 27 investors who focus on Missouri. 1 of them have made recent investments, indicating they are actively deploying capital.

What is the typical check size for Missouri investors?

Check sizes range from $24K to $105.0M, with an average of $6.6M. Check sizes vary by investor type — angels typically write smaller checks while VCs and funds invest larger amounts.

How do I get matched with Missouri investors?

Upload your pitch deck on The Founders' Group landing page for a free AI analysis. Our matching algorithm considers sector focus, stage fit, check size, location, and thesis alignment to recommend investors most likely to be interested in your startup.

Where are most Missouri investors located?

The highest concentration of Missouri investors in our directory is in St. Louis, Kansas City, Saint Louis. However, many investors consider startups regardless of location, especially post-COVID.