The Startup Scene in Pennsylvania
Browse the Pennsylvania startup ecosystem featuring 98 investors and startups. Our directory includes 93 angel investors and VCs with an average check size of $8.7M, plus 5 startups across all sectors. 4 investors are actively investing, and 0 startups are generating revenue.
Startups (5)
View all Pennsylvania startups →Trace Orthopedics
Adam Greenspan
Philadelphia, PA
Millions of people in the U.S. experience tendon injury each year, with over 300,000 undergoing surgery for tendon repair. Surgery involves operating room time, anesthesia, and associated expense,...
Flat5
Scott Noerr
PA
Fragmentation in freight logistics: no single secure, transparent platform connecting shippers, brokers, and drivers causing staffing bloat and empty miles.
Noerr Trucking
Scott Noerr
Pennsylvania
Investors (93)
View all Pennsylvania investors →First Round Capital
First Round Capital
Philadelphia, Pennsylvania
US Innovative Technology Fund
US Innovative Technology Fund
Pittsburgh, Pennsylvania
Synapse Investment
Synapse Investment
Wayne, Pennsylvania
Osage Venture Partners
Osage Venture Partners
Bala Cynwyd, PA
Osage Venture Partners seeks to invest in determined and creative entrepreneurs that have a unique concept or product. Osage works closely to mentor entrepreneurs, and assists them in building...
Novitas Capital
Novitas Capital
Wayne, PA
Novitas Capital ([formerly PA Early Stage Partners](http://novitascapital.com/news/novitas_20071114.html) is a venture capital firm that prospers because of their investment philosophy, their strong...
BioAdvance
BioAdvance
Philadelphia, PA
BioAdvance provides funding to startup life sciences companies in Southeastern Pennsylvania through its $20 million Greenhouse Fund. We invest in therapeutics, devices, diagnostics and platform...
Mid Atlantic Angel Fund
Mid Atlantic Angel Fund
Philadelphia, PA
The Mid-Atlantic Angel Group Fund I, LP (MAG) was created to bridge the gap between angel funding and institutional venture capital funding serving the Greater Philadelphia Region. This...
Merion Investment Partners
Merion Investment Partners
Radnor, PA
Merion is a mezzanine capital fund that defines its target market through a matrix broken down between change of control and growth financing for both equity sponsored and unsponsored transactions....
Valley Capital Partners Direct Invest
Valley Capital Partners Direct Invest
Pittsburgh, Pennsylvania
Ben Franklin Technology Partners of Northeastern Pa
Ben Franklin Technology Partners of Northeastern Pennsylvania
Bethlehem, PA
Regional economic development investor providing capital, business expertise and incubator support to early-stage technology companies and manufacturers across a 21-county territory in Northeastern...
Broad Street Angels
Broad Street Angels
Philadelphia, PA
Broad Street Angels is an angel investment group and affinity club of the Union League of Philadelphia focused on investing in promising startups across the Mid-Atlantic region of the United States....
Alpha Ascent Sprout
Alpha Ascent Sprout
Philadelphia, Pennsylvania
KohFounders Formation Fund
KohFounders Formation Fund
Willow Grove, Pennsylvania
GLOBAL STRATEGIC MOBILITY FUND
GLOBAL STRATEGIC MOBILITY FUND
Ambler, Pennsylvania
Aberdeen Asset Management
Aberdeen Asset Management
Philadelphia, PA
Aberdeen Asset Management PLC is a global investment management group, managing assets for both institutional and retail clients from offices around the world. Their mission is to deliver strong fund...
DreamIt Ventures
DreamIt Ventures
Philadelphia, PA
DreamIt Ventures is a venture capital firm specializing in incubation and seed investments. The firm seeks to invest between $10,000 and $30,000 in each company that goes through one of its...
Susquehanna Growth Equity
Susquehanna Growth Equity
Bala Cynwyd, PA
Susquehanna Growth Equity, LLC (SGE) is a private equity group investing in growth capital and buyout opportunities in financial technology, information services, and software. We utilize our...
SCP Partners
SCP Partners
Wayne, PA
SCP Partners is a principal investment firm specializing in early stage companies with exceptional technology or other proprietary advantages that are poised to capitalize on major market trends;...
Ben Franklin Technology Partners of Southeastern Pennsylvania
Ben Franklin Technology Partners of Southeastern Pennsylvania
Philadelphia, PA
Ben Franklin Technology Partners of Southeastern Pennsylvania offers technology-based economic development programs.
LLR Partners
LLR Partners
Philadelphia, PA
LLR Partners, a leading private equity firm based in Philadelphia, Pennsylvania, provides capital to middle market growth companies with proven business models in a broad range of industries. With...
NextFab Ventures
NextFab Ventures
Philadelphia, PA
Pre-seed, hardware-focused investor and product development center that provides seed capital (initial $57,500), hands-on engineering/product development support, business coaching, access to...
Draper Triangle Ventures
Draper Triangle Ventures
Pittsburgh, PA
[Draper Triangle Ventures](http://www.crunchbase.com/financial-organization/draper-fisher-jurvetson) is the Midwest-based Network Partner of Draper Fisher Jurvetson.
Internet Capital Group
Internet Capital Group
Radnor, PA
From its inception in 1996, ICG has built an outstanding management team, deep industry expertise and a powerful network of partner companies. Their business model was designed to leverage their...
Milestone Partners
Milestone Partners
Radnor, PA
Milestone Partners, founded in 1995, is a private equity firm that partners with management to make control equity investments in LBOs and recapitalizations of lower middle market businesses....
Mid-Atlantic Venture Funds
Mid-Atlantic Venture Funds
Bethlehem, PA
The Mid-Atlantic Venture Funds are four private venture capital partnerships (the first two were called NEPA Venture Funds) with approximately $200 million under management. Their primary investment...
Mentor Capital Partners
Mentor Capital Partners
Yardley, PA
MENTOR's investment criteria are not confined by heavy reliance on certain industries. The existing portfolio and areas of interest encompass a wide variety of areas: * Business and Financial...
Newlin Investment Company
Newlin Investment Company
Sewickley, PA
Newlin Investment Company characterizes itself as a longer term investor based on specific performance goals to create substantial value for the company & the fund. Capital investment in selected...
MissionOG
MissionOG
Devon, PA
MissionOG provides human and financial capital to build B2B companies that have proven feasibility. We apply our experience and capabilities to a group of highly skilled and passionate entrepreneurs...
Benjamin Franklin Technology Partners
Benjamin Franklin Technology Partners
University Park, PA
Ben Franklin has provided the Capital, Knowledge and Networks that help innovative enterprises compete in the global marketplace, generating wealth and supporting regional economic growth. Ben...
Carnegie Mellon University
Carnegie Mellon University
Pittsburgh, PA
Carnegie Mellon University is a global research university with more than 11,000 students, 84,000 alumni, and 4,000 faculty and staff. Recognized for its world-class arts and technology programs,...
Gabriel Investments
Gabriel Investments
Philadelphia, PA
Gabriel Investments is a venture company that invests in businesses in Philadelphia and its surrounding areas.
BlueTree Capital Group
BlueTree Capital Group
Wexford, PA
BlueTree Allied Angels is a regional group of accredited investors who invest in regional early-stage companies. This members-only organization is designed to operate as a network of private equity...
The Musser Group
The Musser Group
Wayne, PA
The Musser Group was started by Warren V. "Pete" Musser a legend in the venture capital and private equity business. The Musser Group is a new type of private equity company created to help...
Berkshire Ventures LLC
Berkshire Ventures LLC
Philadelphia, PA
Berkshire Ventures LLC is a financial organization. Nothing is publicly known about the organization other than this announcement (if there is one--check the sources section at the bottom). If you...
Hamilton Lane
Hamilton Lane
Bala Cynwyd, PA
Hamilton Lane is a firm that provides private equity investment management services.
Clearwater Capital Management
Clearwater Capital Management
Sewickley, PA
Clearwater Capital is a privately held fund management firm dedicated to investing in private ventures and market-neutral hedge opportunities. Clearwater's investment approach combines fundamental...
BlueTree Allied Angels
BlueTree Allied Angels
Wexford, PA
BlueTree Allied Angels is a regional group of accredited investors who invest in regional early-stage companies. This members-only organization is designed to operate as a network of private equity...
SIG
SIG
Bala Cynwyd,, PA
Since its inception in 1987, the Susquehanna International Group of Companies (SIG)* has grown from a trading firm on the Philadelphia Stock Exchange to one of the largest privately held financial...
GIV Venture Partners
GIV Venture Partners
Radnor, PA
GIV, they're a team of individuals with completely diverse backgrounds. They have partners who have helped build the very infrastructure that powers today's Internet and payment processing machines,...
Xandra Laskowski
Xandra Laskowski
Kutztown, PA
We inspire women to learn more about the angel investing world by offering education and access to early stage companies looking for investors. Prospective members are invited to attend one meeting...
TL Ventures
TL Ventures
Wayne, PA
With over $1.5 billion under management, TL Ventures have been actively engaged in the business of venture capital since 1988, investing in over 200 companies to date. Their network of approximately...
Goldin Ventures
Goldin Ventures
Macungie, PA
Goldin Ventures is a private equity and early stage investment firm focused on investments in technology companies with growth opportunities. In addition to minority ownership investments positions,...
Originate Ventures
Originate Ventures
Bethlehem, PA
Originate Ventures is a venture capital investment firm, targeting early stage product and services companies located in Pennsylvania and the surrounding regions. They focus on investing in...
Nextstage Capital
Nextstage Capital
Audubon, PA
Headquartered just outside of Philadelphia, NextStage Capital focuses on finding undiscovered early stage investment opportunities in the Mid-Atlantic region. With an emphasis on technology software,...
Pennsylvania Small Business Development Center
Kutztown University Small Business Development Center
Kutztown, PA
Wayne K. Barz
Ben Franklin Technology Partners of Northeastern Pennsylvania
Bethlehem, PA
State-backed seed investor focused on early-stage technology companies and innovation-driven manufacturers in Northeastern Pennsylvania. Provides capital, mentorship, and incubation through Ben...
Next Act Fund
Next Act Fund
Pittsburgh, PA
We help women grow their personal wealth by investing in early-stage, women-owned/led companies, thereby positively impacting women, the region, and the nation.
Meakem Becker Venture Capital
Meakem Becker Venture Capital
Sewickley, PA
Meakem Becker Venture Capital was founded in late 2005 by Glen Meakem and Dave Becker. Glen was co-founder, Chairman, and CEO of FreeMarkets, formerly the leading provider of internet deployed...
Osage Partners
Osage Partners
Bala Cynwyd, PA
Osage Partners LLC is a venture capital firm specializing in early stage and mid venture investments. It seeks to invest in life sciences, technology, cleantech, and advanced materials sector. It...
Emerald Stage2 Ventures
Emerald Stage2 Ventures
Philadelphia, PA
Emerald Stage2 Ventures is a Philadelphia-based early stage venture fund that invests in capital-efficient emerging technology companies across Pennsylvania and the Mid-Atlantic region. Emerald...
Will Thomas
Angel Star Ventures
Chadds Ford, PA
We guide innovative entrepreneurs to scale early-stage startups (pre-seed/seed) across technology, healthcare, life sciences, real estate and consumer goods through mentorship, funding support, and a...
Angel Star Ventures
Angel Star Ventures
Chadds Ford, PA
Invest in early-stage, scalable startups where the ASV member network can add operational mentorship and domain expertise. Focus on healthcare, life sciences, real estate, and select technology and...
Phase 2 Investments
Phase 2 Investments
Philadelphia, PA
Value-add boutique growth investors partnering with founders and mid-size VCs to scale software and adjacent verticals toward strategic exits or IPOs. Focus areas include SaaS, software development,...
Yvonne Campos
NextFab Ventures
Philadelphia, PA
NextFab Ventures is a pre-seed stage hardware-focused investor and product development center. We provide hard-tech startups with seed capital, hands-on technical product development support,...
Numoda Capital Innovations
Numoda Capital Innovations
Philadelphia, PA
Numoda Capital Innovations is the investment and financing affiliate of Numoda Corporation and the manager of a new venture fund focused on life sciences companies. The fund is designed to take...
Smithfield Trust
Smithfield Trust
Pittsburgh, PA
Smithfield Trust Company is a mix of the old and the new. Like the trust companies of an older era, they understand the need to deliver the highest level of personal service and to honor customer...
iNetworks
iNetworks
Pittsburgh, PA
Since iNetworks was founded in 1999, they have helped companies and entrepreneurs accelerate their solutions to combine capital, management, and intellectual resources to solve many of the critical...
Phoenix IP Ventures
Phoenix IP Ventures
Philadelphia, PA
Phoenix IP Ventures is a fully integrated Private Equity and Venture Capital Fund which specializes in the Life Sciences, principally in the pharmaceutical sector. The Fund acquires intellectual...
Inverness Graham Investments
Inverness Graham Investments
Newtown Square, PA
Inverness Graham is an operationally focused, lower middle market private equity firm headquartered in suburban Philadelphia. Inverness acquires high growth, innovative manufacturing and service...
Pittsburgh Equity Partners
Pittsburgh Equity Partners
Pittsburgh, PA
Pittsburgh Equity Partners (PEP) is a venture capital fund specifically formed to grow Western Pennsylvania's most promising early-stage companies in the life sciences and information technology...
Mellon Ventures
Mellon Ventures
Pittsburgh, PA
As of March 11, 2007, Mellon Ventures, Inc. was acquired by Goldman Sachs Private Equity Group. Mellon Ventures, Inc. is a principal investment firm. The firm is no longer investing. It specializes...
NewSpring Ventures
NewSpring Ventures
Radnor, PA
[NewSpring Ventures](http://www.crunchbase.com/financial-organization/newspring-ventures) is the venture capital arm of [NewSpring...
Eagle Ventures
Eagle Ventures
Pittsburgh, PA
Eagle Ventures International, Inc. engages in the business of providing next-generation voice over internet protocol (VoIP) services to customers in the consumer and small business markets. Eagle...
Life Sciences Greenhouse of Pennsylvania
Life Sciences Greenhouse of Pennsylvania
Harrisburg, PA
LSGPA partners with a range of institutions, including local research universities, colleges, medical centers, economic development agencies and companies both small and large, to identify needs and...
Liberty Associated Partners
Liberty Associated Partners
Bala Cynwyd, PA
Liberty Associated Partners, L.P. is a principal investment firm specializing in private equity investments. It seeks to invest in the telecommunications, media, internet, and related technology...
Guggenheim Venture Partners
Guggenheim Venture Partners
King of Prussia, PA
Guggenheim Venture Partners (GVP) is a private equity and venture capital firm that is focused on undercapitalized technology companies, with practices in distressed venture capital, early stage...
SCP Vitalife Partners
SCP Vitalife Partners
Wayne, PA
SCP Vitalife is a Life Sciences Fund formed by SCP Partners , a U.S.-based investment organization with over $900 million in venture funds under management, and Vitalife , an experienced venture firm...
Devon Park BioVentures
Devon Park BioVentures
Wayne, PA
Devon Park Bioventures is a venture capital fund targeting investments in therapeutics companies and, in certain cases, medical device, diagnostic and drug discovery technology companies.
SeventySix Captial
SeventySix Captial
West Conshohocken, PA
SeventySix Capital is a seed and early-stage venture capital fund investing in consumer products and services businesses.
Cross Atlantic Capital Partners
Cross Atlantic Capital Partners
Radnor, PA
Cross Atlantic Capital Partners is a venture capital firm with a distinct perspective. They currently manage four venture funds with over $500 million in total capital under management. Raised in...
AlphaLab
AlphaLab
Pittsburgh, PA
AlphaLab is a catalyst for launching and accelerating the growth of the next generation of software, web, mobile and entertainment technology companies. Created by [Innovation...
Element Partners
Element Partners
Radnor, PA
Element Partners invests exclusively in established high growth companies in the energy and clean technology markets. They specifically focus on companies with innovative solutions to global energy,...
NewSpring Capital
NewSpring Capital
Radnor, PA
NewSpring Capital, based in Radnor, Pennsylvania, and Short Hills, New Jersey, is a leading provider of private equity capital to the Mid-Atlantic region. NewSpring Capital currently manages over...
EnerTech Capital
EnerTech Capital
Conshohocken, PA
EnerTech Capital has been successfully investing in energy and clean energy technology companies since 1996. The Firm focuses on early to expansion stage ventures that dramatically improve the...
MentorTech Ventures
MentorTech Ventures
Philadelphia, PA
MentorTech Ventures is an early-stage venture capital fund that invests in information technology, marketing technology and medical device companies with a primary focus on those companies...
Osage University Partners
Osage University Partners
Bala Cynwyd, PA
Osage University Partners is a venture capital fund investing in start-ups that commercialize university research.
Quaker BioVentures
Quaker BioVentures
Philadelphia, PA
Quaker BioVentures is a venture capital firm investing in life science companies. The firm leads investments across the spectrum of the life science industry, including biopharmaceuticals, medical...
Pittsburgh Life Sciences Greenhouse
Pittsburgh Life Sciences Greenhouse
Pittsburgh, PA
The Pittsburgh Life Sciences Greenhouse (PLSG) provides capital investments and customized company formation and business growth services to our regionâs life sciences enterprises. We support...
Safeguard Scientifics
Safeguard Scientifics
Wayne, PA
Safeguard Scientifics provides capital and operational support to growth-stage health care and technology companies.
Adams Capital Management
Adams Capital Management
Sewickley, PA
"Adams Capital Management, Inc. (ACM) is a national venture capital firm specializing in early-stage applied technology investments. Established in 1994, ACM is a lead Series A investor and currently...
Ben Franklin Technology Partners of Northeast Pennsylvania
Ben Franklin Technology Partners of Northeast Pennsylvania
Bethlehem, PA
The Ben Franklin Technology Partners of Northeast Pennsylvania (BFTP/NEP) is part of a state-funded economic development initiative created in 1983. They link early-stage technology firms and...
Innovation Works
Innovation Works
Pittsburgh, PA
Innovation Works invests capital, business expertise and resources into companies with the greatest likelihood of regional economic impact.
Sahil Koul
NA. I am an Individual Investor
PA
Individual angel investor (lawyer). Open to the right fit. Interested in SAAS, marketplace, ecommerce, transactional, licensing, freemium, hardware, agency, usage-based, and subscription business...
Joe Wayman
Petabolix
Philadelphia, PA
Broad Street Angels is an angel investment group and affinity club of the Union League of Philadelphia, focused on investing in promising startup companies in the Mid-Atlantic region. Since 2017, the...
Robin Hood Ventures
Robin Hood Ventures
Philadelphia, PA
Early-stage, Mid-Atlantic focused angel group investing ~$250k–$1M; syndicates with VCs and institutions; sector expertise includes Software/Healthcare IT, Hardtech, Life Sciences, and Consumer.
Keiretsu Forum Southeast
Keiretsu Forum Southeast
King of Prussia, PA
Keiretsu Forum is a global angel investor network (Mid-Atlantic, South-East & Texas regions) that sources, vets, and facilitates investment in early-stage companies across technology, healthcare/life...
Keiretsu Forum Mid-Atlantic
Keiretsu Forum
King of Prussia, PA
Keiretsu Forum Mid-Atlantic is an angel investor network providing vetted early-stage investment opportunities across technology, healthcare/life sciences, biotech, consumer products, energy/green...
Delaware Crossing Investor Group
Delaware Crossing Investor Group
Philadelphia, PA
DCIG is an angel investor group focused on early-stage, high-growth companies in the Mid-Atlantic/Greater Philadelphia region. The group prioritizes strong management teams, attractive market...
412 Venture Fund
412 Venture Fund
Pittsburgh, Pennsylvania
412 Venture Fund is an early-stage VC based in Pittsburgh investing nationwide in technology and technology-enabled companies. They focus on AI/ML, B2B SaaS, robotics, advanced materials, sensors,...
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About the Pennsylvania Startup Ecosystem
Pennsylvania is home to a thriving startup ecosystem with 93 investors and 5 startups in our directory. Key hubs include Philadelphia, Pittsburgh, Wayne.
The most active sectors in Pennsylvania include HEALTHCARE SAAS, BIO HEALTHCARE, DIGITAL HEALTH. 4 investors have made recent investments, showing strong capital deployment activity in the region.
Local investors offer advantages beyond capital — regional network effects, knowledge of local market dynamics, and introductions to customers and partners. Geographic proximity often leads to more engaged board members and advisors.
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