The Startup Scene in South Carolina

Browse the South Carolina startup ecosystem featuring 14 investors and startups. Our directory includes 13 angel investors and VCs with an average check size of $3.7M, plus 1 startups across all sectors. 5 investors are actively investing, and 0 startups are generating revenue.

13
Investors
1
Startups
$3.7M
Avg Check
0%
With Revenue
Greenville
Top City
38%
Active Investors

LaunchPad GVL

William D Taylor IV

Greenville, SC

RepeatPrior Exit

Jeff Carollo

Charleston Angel Partners

Angel

Mount Pleasant, SC

Providing capital, counsel, and resources to empower early stage founders. CAP invests in high-performing founders across diverse industries with emphasis on market-product fit and...

Moderately Active42 portfolio co.

Ataraxia Do It

Ataraxia Do It

VC

Spartanburg, South Carolina

Exploring

SC Launch

SC Launch

VC

Columbia, SC

Check: $100K – $30.0M

Created to facilitate applied research, product development and commercialization programs, and to strengthen South Carolina's Knowledge Economy by creating high wage-earning jobs. SC Launch provides...

Exploring13 portfolio co.

Upstate Carolina Angel Network

Upstate Carolina Angel Network

VC

Greenville, SC

Check: $1.0M – $30.0M

The Upstate Carolina Angel Network invests in start-up and early stage high-growth businesses in the Southeastern United States.

Exploring19 portfolio co.

NextStart

NextStart

Corporate

Greenville, SC

NextStart is a South Carolina-based startup incubator. It runs summer immersion programs in which startup entrepreneurs receive funding, mentoring, hands-on learning opportunities, and further...

Exploring4 portfolio co.

HMS Ventures

HMS Ventures

VC

Richburg, SC

Check: $3.2M – $13.6M

Hms Ventures, Llc is a private company categorized under Food Stores and located in Richburg, SC. Current estimates show this company has an annual revenue of $3,300,000 and employs a staff of...

Exploring1 portfolio co.

VentureSouth

VentureSouth

Syndicate

Greenville, South Carolina

Check: $250K – $1.0M

VentureSouth backs early-stage ventures in the Southeastern United States. Industry-agnostic but typically technology-driven; looks for scalable, capital-efficient companies with early revenue or...

Exploring15 portfolio co.

The Iron Yard

The Iron Yard

Corporate

Greenville, SC

Check: $20K – $1.5M

The Iron Yard is a steam engine of creative people. You’ll find everyone from designers, hackers and teachers to makers, artists, and writers. We love building businesses and projects, and our fuel...

Exploring16 portfolio co.

Victoria Park Capital

Victoria Park Capital

VC

Hilton Head Island, SC

Check: $2.2M – $3.0M

Victoria Capital Management is a privately-owned firm providing institutional investment management, wealth management and witness services. They have experience in managing equities and fixed...

Exploring15 portfolio co.

Austin Saggus

AAA Auto Motor Club

GOVERNMENT

Summerville, SC

Check: $200K – $300K

SC Launch Inc., the investment affiliate of South Carolina Research Authority (SCRA), invests primarily in South Carolina-based startups across Information Technology, Life Sciences, and Advanced...

Exploring34 portfolio co.

Roman Sandoval

Allosense, Inc.

Angel

SC

SC Launch Inc. is the investment affiliate of SCRA, focused on accelerating technology-enabled growth in South Carolina by investing in early-stage, high-impact technology startups. The fund supports...

Exploring66 portfolio co.

South Carolina Research Authority (SCRA)

South Carolina Research Authority

GOVERNMENT

Summerville, SC

Check: $100K – $300K
AI MLBIOTECHHEALTHCARE SAAS+3

Public, nonprofit organization that supports South Carolina-based academic and technology startups via grants, coaching, facilities, and investments through its affiliate SC Launch, Inc.; focuses on...

Exploring14 portfolio co.

Charleston Angel Partners

Charleston Angel Partners

Angel

Mount Pleasant, SC

Check: $250K – $2.0M
FINTECHB2B SAASBIOTECH+4

Charleston Angel Partners (CAP) is a boutique angel investment group (est. 2004) that provides capital, counsel, and resources to early-stage founders. CAP focuses on high-performing teams across...

Exploring32 portfolio co.

Explore South Carolina

About the South Carolina Startup Ecosystem

South Carolina is home to a thriving startup ecosystem with 13 investors and 1 startups in our directory. Key hubs include Greenville, Mount Pleasant, Summerville.

The most active sectors in South Carolina include BIOTECH, B2B SAAS, CLIMATE ENERGY SUSTAINABILITY. 5 investors have made recent investments, showing strong capital deployment activity in the region.

Local investors offer advantages beyond capital — regional network effects, knowledge of local market dynamics, and introductions to customers and partners. Geographic proximity often leads to more engaged board members and advisors.

Frequently Asked Questions

How many investors and startups are in South Carolina?
We track 13 investors and 1 startups in South Carolina. 5 investors have made recent investments, and 0 startups are generating revenue.
What is the typical check size for investors in South Carolina?
The average check size among investors in South Carolina is $3.7M. Check sizes vary by investor type — angels typically write smaller checks while VCs and funds invest larger amounts.
How do I connect with investors in South Carolina?
Upload your pitch deck on The Founders' Group landing page for a free AI analysis. Our matching algorithm considers sector focus, stage fit, check size, location, and thesis alignment to recommend the most relevant investors for your startup.
What sectors are most popular in South Carolina?
The most active sectors in South Carolina based on our data include BIOTECH, B2B_SAAS, CLIMATE_ENERGY_SUSTAINABILITY. However, investors and startups in our directory span all major sectors.
Which cities in South Carolina have the most startup activity?
The highest concentration of investors and startups in South Carolina is in Greenville, Mount Pleasant, Summerville. These cities have the strongest local ecosystems for fundraising and startup growth.

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