St. Louis Startup Scene

Explore the St. Louis, Missouri startup ecosystem with 9 investors and startups. Our directory features 9 angel investors and VCs alongside 0 startups actively building in St. Louis. 0 investors have made recent investments, and 0 startups are generating revenue.

Investors

Startups

$7.5M

Avg Check

With Revenue

St. Louis

Top City

Active Investors

Investors (9)

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Cultivation Capital

St. Louis, MO

Check: $100K – $6.5M

Cultivation Capital is a venture capital firm managed by team of serial entrepreneurs. The firm's goal is to take revenue-generating businesses to the next level with help from the General Partners....

Exploring9 portfolio co.

Website

Mariner Capital Ventures

St. Louis, MO

Check: $2.4M – $8.0M

Mariner Capital Ventures (MCV) is a $10 million start-up, angel, and early stage investment fund. MCV targets new and young companies that design innovative and competitive products and services....

Exploring2 portfolio co.

Website

RiverVest

St. Louis, MO

Check: $750K – $46.0M

RiverVest Venture Partners is a venture capital firm focused on identifying and shaping early-stage life science companies to create significant shareholder value. With hands-on, high-level expertise...

Exploring19 portfolio co.

Website

Arch Grants

Corporate

St. Louis, MO

Check: $50K – $110K

Arch Grants is an international business plan competition established to attract entrepreneurs in any field to launch new, innovative businesses in St. Louis. Grant recipients receive up to $50,000,...

Exploring9 portfolio co.

Website

St. Louis Arch Angels

St. Louis, MO

Check: $138K – $8.5M

The mission of the St. Louis Arch Angels is to provide opportunities for their members to obtain outstanding financial returns by investing in early-stage companies with high growth potential in the...

Exploring11 portfolio co.

Website

Oakwood Medical Investors

St. Louis, MO

Check: $2.1M – $30.0M

Oakwood Medical Investors is a life science venture capital fund formed to invest in development stage medical device, biotechnology, pharmaceutical and medical service companies. Target portfolio...

Exploring4 portfolio co.

Website

Prolog Ventures

St. Louis, MO

Check: $500K – $15.3M

Venture capital firm specializing in life sciences. Since launch in 2001, they have supported more than 25 young companies. Prolog invests in traditional healthcare opportunities as well as emerging...

Exploring20 portfolio co.

Website

BioGenerator

St. Louis, MO

Check: $75K – $4.0M

The BioGenerator, the non-profit venture development organization of BioSTL, facilitates the formation of successful, sustainable bioscience companies in the St. Louis region. It provides start-up...

Exploring31 portfolio co.

Website

Melissa Walker

Graematter

St. Louis, MO

Exploring2 portfolio co.

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About St. Louis's Startup Scene

St. Louis, Missouri has 9 investors and 0 startups in our community.

Frequently Asked Questions

How many investors and startups are in St. Louis, Missouri?

We track 9 investors and 0 startups in St. Louis, Missouri. 0 investors have made recent investments, and 0 startups are generating revenue.

What is the typical check size for investors in St. Louis, Missouri?

The average check size among investors in St. Louis, Missouri is $7.5M. Check sizes vary by investor type — angels typically write smaller checks while VCs and funds invest larger amounts.

How do I connect with investors in St. Louis, Missouri?

Upload your pitch deck on The Founders' Group landing page for a free AI analysis. Our matching algorithm considers sector focus, stage fit, check size, location, and thesis alignment to recommend the most relevant investors for your startup.

Is St. Louis a good place to raise funding?

With 9 investors in our directory, St. Louis has an active funding ecosystem. 0 investors have made recent investments, suggesting active capital deployment. Geographic proximity to investors can be advantageous for angel and early-stage fundraising.

Which cities in Missouri have the most startup activity?

The highest concentration of investors and startups in Missouri is in St. Louis. These cities have the strongest local ecosystems for fundraising and startup growth.

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